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Scheduled NeoLINK Downtime – Sunday, 10/19/2025 - 11:00 PM ET (8:00 PM PT)

NeoLINK will be undergoing planned maintenance on Sunday, 10/19/2025 at 11:00 PM EST (8:00 PM PST) with an estimated downtime of less than 45 minutes.

Please get in touch with Client Services at 866.776.5907, option 3 with any questions.

Thank you,

NeoGenomics Laboratories – Digital Technology Solutions (DTS)

10/13/2025

Need access to NeoLink? Contact your Sales rep or our Client Services team at 866.776.5907, Option 3

October 13, 2025

Molecular

We are proud to announce new NGS assays for the MPN-associated biomarkers (JAK2, CALR, and MPL) that is now available as of today, Monday, October 13, 2025.

The NGS assays will immediately replace the current tests that are performed by PCR, bi-directional sequencing and/or fragment length analysis (FLA). See below table.
- Orders of the old tests will be automatically accessioned for the new tests.
Benefits
- Lower Limit of Detection: 1% for JAK2 V617F, 2% for all others
- More exon coverage on JAK2 gene
- Faster TAT: 7 days for all tests
Test names will change to reflect the change in methodology and accurately describe the scope of JAK2 testing. The updates are highlighted in bold in the table.
CPT codes and pricing will remain the same.
NYS Approval: The NGS versions will not be NYSDOH-approved by launch date. NYS orders will be processed with the old methodology until approval is received for the NGS assays.
For Interface Clients: This test update will involve a change in test names and codes. Please refer to the Interface Updates section for more info.

Old Test Names	Old Methodology	New Test Names	New Methodology
MPN JAK2 V617F with Sequential Reflex to JAK2 Exon 12-13, CALR, and MPL	PCR/Bi-directional Sequencing/FLA	MPN JAK2 V617F with Sequential Reflex to JAK2 Exon 12-15, CALR, and MPL	NGS
JAK2 V617F Mutation Analysis – Qualitative	PCR/Bi-Directional Sequencing	JAK2 V617F Mutation Analysis by NGS	NGS
JAK2 Exon 12-13 Mutation Analysis	PCR/Bi-directional Sequencing	JAK2 Extended (Exon 12-15 non-V617F) Mutation Analysis by NGS	NGS
Calreticulin (CALR) Mutation Analysis	FLA/Bi-directional Sequencing	CALR Mutation Analysis by NGS	NGS
MPL Mutation Analysis	Bi-directional Sequencing	MPL Mutation Analysis by NGS	NGS

Note: This methodology change does NOT apply to JAK2 V617F Mutation Analysis – Quantitative. The quantitative test remains the same.

Online Ordering, paper requisition forms, and website will be updated and available on 10/13/2025.

For a complete list of recent test updates, click here for a downloadable document to view the impacted interface test codes.

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